1.King Charles knew if the Russians began to settle the area, Spain might lose control of California forever.

lose control of失去对…的控制

例句：He lost all control of himself.
      他完全失去了自制力。

2.In time, the road from mission San Diego de Alcala to mission San Francisco Solano was given a name.

in time迟早, 最后

例句：In time you'll forget him.
      你迟早会忘了他的。

3.In the eighteen forties, Mexico had trouble controlling the American settlers in California.

have trouble doing做……有困难

例句：I have trouble swallowing food.
      我吞咽有困难。

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