tick somebody off 或者tick off somebody，意为“使……生气(to make someone angry)"

例句：

You seem really ticked off. What's up?
你好像很生气，出什么事了？

It just ticks me off to think that anyone who wants to can read my e-mail.
其他人能随意查看我的电子邮件，想起来很让我生气。