Make a difference 有影响

Make a difference 是指会对现有的情况造成差别，跟以往不同。

A：I know you need some financial help. If I give you a raise, will it help?
我知道你需要一些经济支援。若我给你加薪会有帮助吗？
B：Well, it will certainly make a difference. 呃，这将会大有帮助。

Make a difference 也可以指对于现状有所不满，希望未来能使大环境产生变化。
A：What do you want to do with your job? 你这一生要做什么？
B：I want to be a nurse so that I can make a difference. 我要当护士让自己力挽狂澜。