The boss is driving me nuts.

老板快把我逼疯了。

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drive原表示“开车”，亦做“逼迫，迫使”解，用法如下：drive sb+adj.迫使某人……的。
例：
His sister was driving him nuts with her constant phone calls.
他妹妹不断地打电话来，快把他逼疯了。