Chygrynski had to be replaced by Gerard Pique after 55 minutes of the Spanish first division game, which Barcelona won 2-0, suffering from problems in his left knee.
He underwent tests on returning to Barcelona this Sunday morning and the club issued an official communique explaining the extent of his injury.
The Ukrainian, who cost 25 million euros from Shakthar Donetsk at the end of the summer, has suffered an elongation of his knee ligaments and will be out of action for the next three weeks.
That means he will miss Tuesday' s Champions League match against fellow countryman Dynamo Kiev as well as his country's vital World Cup qualifying game against England on October 10.
Meanwhile Thierry Henry is suffering a groin strain and is also doubtful for Tuesday' s match.
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